Philippe KASTNER and Susan CHAN

Project Title: Defining the function of the Helios transcription factor in hematopoietic stem cell ageing.

Work Package(s) to which it is related : WP1, WP2.

Objectives and scientific expected results:
i) to demonstrate that Helios controls the age-dependent evolution of HSCs;
ii) to demonstrate Helios impact on hematopoietic cell fitness with age.