ESR Publications

Athanasios Oikonomou, Luigia Valsecchi, Manuel Quadri, Titus Watrin, Katerina Scharov, Simona Procopio, Jia-Wey Tu, Melina Vogt, Angela Maria Savino, Daniela Silvestri, Maria Grazia Valsecchi, Andrea Biondi, Arndt Borkhardt, Sanil Bhatia, Giovanni Cazzaniga, Grazia Fazio, Michela Bardini, Chiara Palmi.
High-throughput screening as a drug repurposing strategy for poor outcome subgroups of pediatric B-cell precursor Acute Lymphoblastic Leukemia.
Biochemical Pharmacology 2023, DOI: https://doi.org/10.1016/j.bcp.2023.115809

Natalia Skinder, Irene Sanz Fernández, Albertien Dethmers-Ausema, Ellen Weersing, Gerald de Haan
CD61 identifies a superior population of aged murine HSCs and is required to preserve quiescence and self-renewal, Blood Advances 2023
DOI: 10.1182/bloodadvances.2023011585, https://pubmed.ncbi.nlm.nih.gov/37939263/

Christina Pitsillidou, Ivan Muradore , Elena Pontarini, Milena Bertolotti, Alessandra Roberto
A redox-based characterization of human immune cell subsets by polychromatic flow cytometry
DOI: 10.1016/j.xpro.2023.102632 ,     https://pubmed.ncbi.nlm.nih.gov/37838948/

Guillermo Fernandez Rodriguez, Bianca Cesaro, andAlessandro Fatica
Multiple Roles of m6A RNA Modification in Translational Regulation in Cancer
https://doi.org/10.3390/ijms23168971   ,  https://www.mdpi.com/1422-0067/23/16/8971

Ludovica Proietti, Gabriele Manhart, Elizabeth Heyes, Selina Troester, Florian Grebien
Arrayed CRISPR/Cas9 Screening for the Functional Validation of Cancer Genetic Dependencies
DOI: 10.21769/BioProtoc.4577  ,   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797365/

-Yu Wei Zhang, Julian Mess, Nadim Aizarani, Pankaj Mishra, Carys Johnson , Mari Carmen Romero-Mulero, Jasmin Rettkowski, Katharina Schönberger, Nadine Obier, Karin Jäcklein, Nadine M Woessner, Maria-Eleni Lalioti, Talia Velasco-Hernandez , Katarzyna Sikora, Ralph Wäsch, Bernhard Lehnertz, Guy Sauvageau, Thomas Manke, Pablo Menendez, Sebastian Gottfried Walter, Susana Minguet, Elisa Laurenti, Stefan Günther, Dominic Grün, Nina Cabezas-Wallscheid
Hyaluronic acid-GPRC5C signalling promotes dormancy in haematopoietic stem cells
DOI: 10.1038/s41556-022-00931-x  ,  https://pubmed.ncbi.nlm.nih.gov/35725769/

-Ifat Geron, Angela Maria Savino, Hila Fishman, Noa Tal, John Brown, Virginia A. Turati,4 Chela James, Jolanda Sarno, Michal Hameiri-Grossman, Yu Nee Lee,Avigail Rein, Hillary Maniriho, Yehudit Birger, Anna Zemlyansky, Inna Muler, Kara L. Davis, Victoria Marcu-Malina, Nicole Mattson, Oren Parnas, Rabea Wagener, Ute Fischer, João T. Barata, Catriona H. M. Jamieson, Markus Müschen, Chun-Wei Chen, Arndt Borkhardt, Ilan Richard Kirsch, Arnon Nagler, Tariq Enver, and Shai Izraeli
An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia
DOI: 10.1038/s41467-022-28218-7  ,  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814001/

-Chiara Palmi, Silvia Bresolin, Stefanie Junk, Grazia Fazio, Daniela Silvestri, Marketa Zaliova, Athanasios Oikonomou, Katerina Scharov, Martin Stanulla, Anja Moericke, Martin Zimmermann, Martin Schrappe, Barbara Buldini, Sanil Bhatia, Arndt Borkhardt, Claudia Saitta, Marta Galbiati, Michela Bardini, Luca Lo Nigro, Valentino Conter, Maria Grazia Valsecchi, Andrea Biondi, Geertruy Te Kronnie, Gunnar Cario, Giovanni Cazzaniga
Definition and Prognostic Value of Ph-like and IKZF1plus Status in Children With Down Syndrome and B-cell Precursor Acute Lymphoblastic Leukemia
DOI: 10.1097/HS9.0000000000000892  , https://pubmed.ncbi.nlm.nih.gov/37304931/

– Christina Pitsillidou, Sandra Alonso-Rubido, Andrea Ávila-Ávila, Mari Carmen Romero-Mulero, Agata Labedz, Athanasios Oikonomou, Ludovica Proietti, Maria Eleni Psychoyiou, Clara Tellez-Quijorna, Maniriho Hillary, Eirini Sofia Fasouli, Guillermo Fernández-Rodríguez, Natalia Giner-Laguarda, Natalia Skinder, Chiara Taroni, John Strouboulis, Eleni Katsantoni, Antonella Ellena Ronchi (2022).
A Journey Into the Unknown: PhD Students in a European Training Network on Age-related Changes in Hematopoiesis Conduct Their Project During a Global Pandemic. Hemasphere. 2022 Jul 29;6(8):e763. doi: 10.1097/HS9.0000000000000763.   ,   share the Tweet
-Valentina Pastori, Serena Pozzi, Agata Labedz, Sajeela Ahmed, Antonella Ellena Ronchi
Role of Nuclear Receptors in Controlling Erythropoiesis
DOI: 10.3390/ijms23052800   , https://pubmed.ncbi.nlm.nih.gov/35269942/

-Giovanni Cova, Chiara Taroni, Marie-Céline Deau, Qi Cai, Vincent Mittelheisser, Muriel Philipps, Matthieu Jung, Marie Cerciat, Stéphanie Le Gras, Christelle Thibault-Carpentier,Bernard Jost, Leif Carlsson, Angela M. Thornton, Ethan M. Shevach, Peggy Kirstetter, Philippe Kastner, Susan Chan
Helios represses megakaryocyte priming in hematopoietic stem and progenitor cells
DOI: 10.1084/jem.20202317  ,   https://pubmed.ncbi.nlm.nih.gov/34459852/

-Pia Sommerkamp, Mari Carmen Romero-Mulero, Andreas Narr, Luisa Ladel, Lucie Hustin, Katharina Schonberger, Simon Renders, Sandro Altamura, Petra Zeisberger, Karin Jacklein, Daniel Klimmeck, Alejo Rodriguez-Fraticelli, Fernando D. Camargo, Leïla Perie, Andreas Trumpp, and Nina Cabezas-Wallscheid. *co-first authors.
Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells
https://doi.org/10.1182/blood.2020007876   ,   https://pubmed.ncbi.nlm.nih.gov/33754628/

-Katharina Schoenberger, Nadine Obier, Mari Carmen Romero-Mulero, Pierre Cauchy, Julian Mess, Polina V. Pavlovich, Yu Wei Zhang, Michael Mitterer, Jasmin Rettkowski, Maria-Eleni Lalioti, Karin Jacklein, Jonathan D. Curtis, Betty Feret, Pia Sommerkamp, Claudia Morganti, Keisuke Ito, Norbert B. Ghyselinck, Eirini Trompouki, Joerg M. Buescher, Erika L. Pearce, and Nina Cabezas-Wallscheid
Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity. 
https://doi.org/10.1016/j.stem.2021.10.002  ,  https://pubmed.ncbi.nlm.nih.gov/34706256/

-Arthur Flohr Svendsen, Daozheng Yang, KyungMok Kim, Seka Lazare, Natalia Skinder, Erik Zwart, Anna Mura-Meszaros, Albertina Ausema, Björn von Eyss, Gerald de Haan, Leonid Bystrykh
A comprehensive transcriptome signature of murine hematopoietic stem cell aging, Blood, 2021
DOI: https://doi.org/10.1182/blood.2020009729
https://pubmed.ncbi.nlm.nih.gov/33876187/

-Yu Wei Zhang, Talia Velasco-Hernandez, Julian Mess, Maria-Eleni Lalioti, Mari Carmen Romero-Mulero, Nadine Obier, Nikolaos Karantzelis, Jasmin Rettkowski, Katharina Schönberger, Noémie Karabacz, Karin Jäcklein, Tatsuya Morishima, Juan Luis Trincado, Paola Romecin, Alba Martinez-Moreno, Hitoshi Takizawa, Khalid Shoumariyeh, Simon Renders, Robert Zeiser, Heike L. Pahl, François Béliveau, Josée Hébert, Bernhard Lehnertz, Guy Sauvageau, Pablo Menendez, Nina Cabezas-Wallscheid
GPRC5C Drives Branched-Chain Amino Acid Metabolism in Leukemogenesis, Blood Advances, 2023
https://doi.org/10.1182/bloodadvances.2023010460
https://pubmed.ncbi.nlm.nih.gov/37639313/

– Barbarani, G., & Labedz, A., Ronchi, A. E. (2020).
β-hemoglobinopathies: the test bench for genome editing-based therapeutic
strategies. Frontiers in Genome Editing, 2, 16.
DOI: 10.3389/fgeed.2020.571239

– Barbarani, G., Labedz, A., Stucchi, S., Abbiati, A., & Ronchi, A. E. (2021).
Physiological and Aberrant γ-Globin Transcription During Development. Frontiers in Cell and Developmental Biology, 9, 563.
DOI: 10.3389/fcell.2021.640060

Giner-Laguarda, N. & Vidal, M. (2020).
Functions of Polycomb Proteins on Active Targets. Epigenomes, 4(3), 17.
DOI: 10.3390/epigenomes4030017

Fasouli, E. S. & Katsantoni E. (2021).
JAK-STAT in Early Hematopoiesis and Leukemia.
Front. Cell Dev. Biol., 9:669363.
DOI: 10.3389/fcell.2021.669363